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1.
Antiplatelet properties of Pim kinase inhibition are mediated through disruption of thromboxane A2 receptor signaling.
Haematologica
; 106(7): 1968-1978, 2021 07 01.
Article
in English
| MEDLINE | ID: mdl-32467143
2.
Arrestin-3 differentially regulates platelet GPCR subsets.
Platelets
; 31(5): 641-645, 2020 Jul 03.
Article
in English
| MEDLINE | ID: mdl-31684789
3.
Inverse agonism at the P2Y12 receptor and ENT1 transporter blockade contribute to platelet inhibition by ticagrelor.
Blood
; 128(23): 2717-2728, 2016 12 08.
Article
in English
| MEDLINE | ID: mdl-27694321
4.
Protease-Activated Receptor 4 Variant p.Tyr157Cys Reduces Platelet Functional Responses and Alters Receptor Trafficking.
Arterioscler Thromb Vasc Biol
; 36(5): 952-60, 2016 05.
Article
in English
| MEDLINE | ID: mdl-26966273
5.
Characterization of multiple platelet activation pathways in patients with bleeding as a high-throughput screening option: use of 96-well Optimul assay.
Blood
; 123(8): e11-22, 2014 Feb 20.
Article
in English
| MEDLINE | ID: mdl-24408324
6.
Differential endosomal sorting of a novel P2Y12 purinoreceptor mutant.
Traffic
; 14(5): 585-98, 2013 May.
Article
in English
| MEDLINE | ID: mdl-23387322
7.
RhoG protein regulates platelet granule secretion and thrombus formation in mice.
J Biol Chem
; 288(47): 34217-34229, 2013 Nov 22.
Article
in English
| MEDLINE | ID: mdl-24106270
8.
Ticagrelor inverse agonist activity at the P2Y12 receptor is non-reversible versus its endogenous agonist adenosine 5´-diphosphate.
Br J Pharmacol
; 181(1): 21-35, 2024 01.
Article
in English
| MEDLINE | ID: mdl-37530222
9.
Arrestin scaffolds NHERF1 to the P2Y12 receptor to regulate receptor internalization.
J Biol Chem
; 287(29): 24505-15, 2012 Jul 13.
Article
in English
| MEDLINE | ID: mdl-22610101
10.
Molecular mechanisms of platelet P2Y(12) receptor regulation.
Biochem Soc Trans
; 41(1): 225-30, 2013 Feb 01.
Article
in English
| MEDLINE | ID: mdl-23356287
11.
An intact PDZ motif is essential for correct P2Y12 purinoceptor traffic in human platelets.
Blood
; 118(20): 5641-51, 2011 Nov 17.
Article
in English
| MEDLINE | ID: mdl-21937696
12.
Alterations in platelet proteome signature and impaired platelet integrin αIIbß3 activation in patients with COVID-19.
J Thromb Haemost
; 21(5): 1307-1321, 2023 05.
Article
in English
| MEDLINE | ID: mdl-36716966
13.
Regulation of P2Y1 receptor traffic by sorting Nexin 1 is retromer independent.
Traffic
; 11(4): 508-19, 2010 Apr.
Article
in English
| MEDLINE | ID: mdl-20070609
14.
Endomorphin-2: a biased agonist at the µ-opioid receptor.
Mol Pharmacol
; 82(2): 178-88, 2012 Aug.
Article
in English
| MEDLINE | ID: mdl-22553358
15.
A novel thromboxane A2 receptor D304N variant that abrogates ligand binding in a patient with a bleeding diathesis.
Blood
; 115(2): 363-9, 2010 Jan 14.
Article
in English
| MEDLINE | ID: mdl-19828703
16.
Identification and characterization of a novel P2Y 12 variant in a patient diagnosed with type 1 von Willebrand disease in the European MCMDM-1VWD study.
Blood
; 113(17): 4110-3, 2009 Apr 23.
Article
in English
| MEDLINE | ID: mdl-19237732
17.
Tetherin/BST2, a physiologically and therapeutically relevant regulator of platelet receptor signalling.
Blood Adv
; 5(7): 1884-1898, 2021 04 13.
Article
in English
| MEDLINE | ID: mdl-33792632
18.
Pharmacodynamic Comparison of Ticagrelor Monotherapy Versus Ticagrelor and Aspirin in Patients After Percutaneous Coronary Intervention: The TEMPLATE (Ticagrelor Monotherapy and Platelet Reactivity) Randomized Controlled Trial.
J Am Heart Assoc
; 9(24): e016495, 2020 12 15.
Article
in English
| MEDLINE | ID: mdl-33305660
19.
Pathophysiological consequences of receptor mistraffic: Tales from the platelet P2Y12 receptor.
Mol Cell Endocrinol
; 449: 74-81, 2017 07 05.
Article
in English
| MEDLINE | ID: mdl-28212842
20.
Impaired thromboxane receptor dimerization reduces signaling efficiency: A potential mechanism for reduced platelet function in vivo.
Biochem Pharmacol
; 124: 43-56, 2017 Jan 15.
Article
in English
| MEDLINE | ID: mdl-27845050